A novel method for detecting and monitoring the reactive nitrogen species peroxynitrite in normal physiology and human pathology. The invention offers significant advantages over traditional methods for detecting and monitoring the cellular production of peroxynitrite by overcoming limitations of other sensors. This is important because current methods are less sensitive and less robust, especially for studies of living cells such as its involvement in immunology. This invention may yield better information about the effects of peroxynitrite in a variety of diseases including infectious disease, cancer, neurodegeneration, and others.
A novel method for measuring olfactory dysfunction. The method offers significant advantages over the traditional method for measuring olfactory dysfunction such as UPSIT and overcomes many of the limitations and concerns with its affordable, accessible, and user-friendly method to measure olfactory dysfunction using essential oils in alterable concentrations.
A low-cost telemedicine tool featuring a virtual reality (VR) interface has been designed and developed to assist with the evaluation and diagnosis of neurodegenerative disease, thereby enabling greater access to care and earlier diagnosis for patients with neurological disorders; even for those in remote areas, or with limited transportation options.
Small camera/collection device that collects samples all along the surface of the esophagus, increasing disease detection rate.
This invention uses microRNA biomarkers to detect or diagnose Barrett's esophagus, detect dysplasia in Barrett's esophagus, and detect early onset of esophageal cancer.