Category: reagents

Novel ligands designed to activate mu opioid receptors and provide analgesic effects without opioid-related side effects, providing specific insight into the cellular impact of opioid receptor-based activation as related to pain medications.  These ligands could be used as a tool to negate drug tolerance and dependence as well as other adverse side effects.

This method utilizes a novel solid catalyst made specifically for olefin epoxidation. The catalyst utilizes a base in order to allow hydrogen peroxide to be utilized as an oxidant.  Further the system allows for a constant flow of feedstock to flow through the catalyst with minimal leaching of the metal from the catalyst allowing for a longer life of the catalyst.

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The invention is a novel and efficient method to establish new embryonic stem (ES) cell lines from mammalian species and to maintain ES cells at the pluripotent state.

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The invention offers high load reagents and scavengers which combine the physical properties of the silica surface with the inherent tunable properties of the ROMP-derived oligomers.

The invention entails solution conditions that can prolong the recovery and foldability of proteins under non-denaturing conditions in the presence of the tetradecameric GroEL chaperonin. 

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