A device for rapid dialysis of microliter volume liquid samples useful in laboratory-scale dialysis operations.
Novel ligands designed to activate mu opioid receptors and provide analgesic effects without opioid-related side effects, providing specific insight into the cellular impact of opioid receptor-based activation as related to pain medications. These ligands could be used as a tool to negate drug tolerance and dependence as well as other adverse side effects.
This invention provides an improved method for producing a novel interfacing capillary device that is less costly and more durable than existing sheathless devices. This simplified production method does not require sample dilution, etching, or precision hand tools, and is automated and reproducible.
A microfluidic device capable of efficiently isolating exosomes from blood and plasma.
This invention consists of a new hyphenated atomic force microscopy (AFM) technique with whispering gallery mode sensing (WGM), which provides the ability to measure the topography and refractive index of a material simultaneously.
A three-dimensional tumor-in-dish (TID) cell-based assay kit for cancer drug screening that closely replicates actual cellular microenvironments and, therefore, can determine which compounds to move forward for in vivo testing.
Novel chemical compounds for use as antivirals against RSV
The invention provides a "sample-in-answer-out" microfluidic exosome profiling platform which integrates immunoaffinity isolation of plasma exosomes with quantitative detection of both surface and intravesicular markers for characterization of exosomal phenotypes.
The invention offers high load reagents and scavengers which combine the physical properties of the silica surface with the inherent tunable properties of the ROMP-derived oligomers.