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Conjugate compositions that combine a functionalized I-domain peptide covalently bound to multiple signal-1 blocking moieties to reduce type-1 immune responses.

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This invention provides compounds for modulating T-cell pathways and subsequent immunity.

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Piezoelectric composites, as well as methods of making such composites for biomedical applications.
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Novel chemical compounds for use as antivirals against RSV

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A compact anti-rotation device for immobilizing and/or securing bone portions for post-injury healing.

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This invention includes novel methods for creating and isolating regulatory T cells (Tregs) for use in adoptive immunotherapy.  

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This invention is a system to deliver poorly permeable molecules into mammalian cells and avoid the problem of degradation. 

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This invention is a novel composition of matter that facilitates delivery of agents (e.g. diagnostic, therapeutic, imaging, etc.) into cells

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The invention is a method of generating regulatory T-cells from CD4+ naive T-cells in vitro without the use of added cytokines.

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This invention utilizes a delivery system that allows for a biologically relevant moiety to be delivered to a desired cell by utilizing a transporting agent that binds two receptors expressed by that cell. This decreases the toxicity that is shown by the active compound by delivering it only to a targeted cell.

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