All Available Technologies
Conjugate compositions that combine a functionalized I-domain peptide covalently bound to multiple signal-1 blocking moieties to reduce type-1 immune responses.
This invention provides compounds for modulating T-cell pathways and subsequent immunity.
Novel chemical compounds for use as antivirals against RSV
A compact anti-rotation device for immobilizing and/or securing bone portions for post-injury healing.
This invention includes novel methods for creating and isolating regulatory T cells (Tregs) for use in adoptive immunotherapy.
This invention is a system to deliver poorly permeable molecules into mammalian cells and avoid the problem of degradation.
This invention is a novel composition of matter that facilitates delivery of agents (e.g. diagnostic, therapeutic, imaging, etc.) into cells
The invention is a method of generating regulatory T-cells from CD4+ naive T-cells in vitro without the use of added cytokines.
This invention utilizes a delivery system that allows for a biologically relevant moiety to be delivered to a desired cell by utilizing a transporting agent that binds two receptors expressed by that cell. This decreases the toxicity that is shown by the active compound by delivering it only to a targeted cell.