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A handheld surgical device that will allow safe, complete and controlled removal of subretinal fluid during retinal detachment repair surgery.
Selective heat shock protein 90 (Hsp90) and glucose regulated protein 94 (Grp94) inhibitors that can be used to develop an effective therapy for treating primary open angle glaucoma (POAG).
The small molecules in this work represent a novel composition of matter that can be used as either Kappa Opioid Receptor (KOR) agonists or antagonists. Further some of the compounds have been shown to weak agonists making them ideal to explore for the use of addiction.
The invention describes CD44-selective nanovector systems for cancer-targeted delivery of molecular therapeutics.
Broad based label-free systems identify protein stabilizers at physiological or near physiological conditions that specifically inhibit Bacterial Toxin or Viral entry into cells.
This invention is a tubular electrospun scaffold of natural protein gelatin and synthetic polyglycolic acid (PGA) / poly-lactic-co-glycolic (PLGA) polymers in a bioreactor system connected to a flow circuit and seeded with cultured fibroblasts and endothelial cells.
Our researcher at KUMC has developed methods of prediction, diagnosis, and treatment of primary osteoarthritis.
The invention consists of new bi-functional protein inhibitors (“BPIs”) for treatment and diagnostics of autoimmune diseases such as MS and experimental autoimmune encephalomyelitis. The novel BPIs are capable of modulating the immune response towards a TH2 response.
Transmission of blood-borne infections (e.g., HIV) from health care exposures was previously believed to be uncommon. However, multiple outbreaks across the U.S. over the last several years have shed light on this problem. Thousands of individuals exposed to potential blood-borne pathogens. As recently as October 2009, in one of the hospitals in Florida, the nurse routinely used the same bag of saline on multiple patients. In another outbreak in an outpatient oncology clinic in Nebraska, the nurse would reuse a syringe to perform a saline flush. Saline for multiple patients was acquired from a common bag. More than 600 patients were notified and 99 patients were diagnosed with Hepatitis C. These cases all have in common acquisition of saline or a drug from a common container via a contaminated needle and/or syringe. Despite the increasing use of single-dose vials, such outbreaks occur as providers still use these single-dose vials on multiple individuals to reduce costs.
The VestibuGLIDE System represents a new medical device designed to provide therapeutic stimulation of the vestibular system in premature infants.